Despite significant advances in recent decades, synthetic chemistry remains a highly challenging field. Synthesis of novel molecules with unique properties is an essential tool in drug discovery, but remains a time-consuming endeavor that can often be a bottleneck to the overall process. Highly trained synthetic chemists commit a significant amount of time and consideration to route scouting and the optimization of reaction conditions to access novel structures. This reliance on human expertise introduces the potential for errors and biases and is subject to limits in scalability and efficiency. With an increasing demand for novel molecules having specific properties, there is a pressing need to streamline the synthesis process.
In this case study, we present how SYNTHIA™ Retrosynthesis Software and SynpleChem Automated Synthesizer can accelerate the design and synthesis process and boost productivity. Take a look at the full application note as well as additional resources linked below.