Teach retrosynthesis like it’s practiced today
Retrosynthesis is still a creative craft. But students and researchers also need modern decision-support tools so they can explore multiple synthetic pathways, compare tradeoffs, and learn how real labs balance step count, feasibility, and starting material availability.
With SYNTHIA® Retrosynthesis Software, your group can bring computer-assisted synthesis planning into teaching and academic research without turning chemistry decisions into a black box.
Retrosynthesis for Every Lab - SYNTHIA® Lab
Designed for
- Organic chemistry educators (advanced undergrad / graduate)
- Natural product and complex molecule synthesis groups
- Chemical biology and methodology labs
- University departments where library/department procurement manages software access
Preparing the next generation of chemists is not easy
TEACH ROUTE DESIGN, NOT ROTE ANSWERS
Help students learn why one pathway is preferred over another.
EXPOSE STUDENTS TO REAL-WORLD CONSTRAINTS
Cost, safety, step count, protecting groups, and building-block availability.
SUPPORT EARLY-STAGE RESEARCH
Generate route hypotheses faster and spark new disconnection ideas.
WORK COLLABORATIVELY
Share pathway ideas and provide feedback directly in SYNTHIA®
How SYNTHIA® Retrosynthesis Software Helps Academia
1
Explore Multiple Routes
Explore Multiple Routes
Students can explore multiple routes for each target and compare strategy, convergence, feasibility, and tradeoffs instead of settling for a single answer.
2
Plan Practical Routes
Plan Practical Routes
Students can connect route choices to commercially available building blocks, procurement considerations, and shopping lists for realistic teaching and research experiments.
3
Compare Route Tradeoffs
Compare Route Tradeoffs
Students can sort pathways by step count, protecting groups, and published-reaction similarity to explain route tradeoffs in meetings and thesis defenses.
4
Collaborate On Ideas
Collaborate On Ideas
Students can use SYNTHIA® Whiteboard to combine route ideas, capture feedback, and continue collaborative retrosynthesis discussions asynchronously beyond the laboratory.
1
Explore Multiple Routes
Explore Multiple Routes
Students can explore multiple routes for each target and compare strategy, convergence, feasibility, and tradeoffs instead of settling for a single answer.
2
Plan Practical Routes
Plan Practical Routes
Students can connect route choices to commercially available building blocks, procurement considerations, and shopping lists for realistic teaching and research experiments.
3
Compare Route Tradeoffs
Compare Route Tradeoffs
Students can sort pathways by step count, protecting groups, and published-reaction similarity to explain route tradeoffs in meetings and thesis defenses.
4
Collaborate On Ideas
Collaborate On Ideas
Students can use SYNTHIA® Whiteboard to combine route ideas, capture feedback, and continue collaborative retrosynthesis discussions asynchronously beyond the laboratory.
Retrosynthesis for Every Lab - SYNTHIA® Lab
SYNTHIA® Lab is purpose-built for smaller labs and academic teams, offering seamless access to over 12 million commercially available starting materials and building blocks. With its intuitive SaaS platform, no installation required, you can quickly discover novel synthetic pathways for individual targets or entire libraries. Plus, you’ll benefit from SYNTHIA® online trainings and knowledge center, ensuring you get the most out of your retrosynthesis journey.
What you get with SYNTHIA® Lab:
- Automatic retrosynthesis, step-by-step analysis, similarity search
- Collaboration (share/comment), plus whiteboard-style route brainstorming
- Access to a large catalog of commercially available building blocks and reagents via shopping list workflow
Where this fits in your teaching and research
Lecture + discussion
Demonstrate multiple disconnections live, then compare and critique route options.
Problem sets
Assign students to justify route choice based on step count, feasibility, and starting material logic.
Group meeting
Use SYNTHIA® Retrosynthesis Software to accelerate brainstorming and focus discussion on the best next experiment.
Proposal writing
Use pathway options to support feasibility planning for new targets (especially when literature precedent is thin).
Links worth your time
RESOURCES OVERVIEW
A curated hub of webinars and publications you can use to build lectures, assignments, and group discussions around real retrosynthesis decisions.
JOURNAL PAPERS
Peer-reviewed examples that connect textbook disconnections to contemporary computer-assisted planning and real synthesis outcomes.
SYNTHIA® LAB
A practical starting point for universities and non-profits that want access for a small team without an enterprise rollout.
Reach out to us
Quickly go from imagining what’s possible to testing what’s probable with a license that fits your needs.
SYNTHIA® News
in Your Inbox