WEBINAR:
Synthesis Automation with SYNTHIA® & SynpleChem

Despite significant advances in recent decades, synthetic chemistry remains a highly challenging field. Synthesis of novel molecules with unique properties is an essential tool in drug discovery, but remains a time-consuming endeavor that can often be a bottleneck to the overall process. With an increasing demand for novel molecules with specific properties, there is a pressing need to streamline the synthesis process.
The application of a customized set of search parameters in SYNTHIA® can be used to easily plan efficient routes to target molecules that can be quickly executed using Synple automated synthesis technology. This allows the chemist to save manual time required for route planning and searching for appropriate starting materials as well as in bench execution, ultimately accelerating the drug discovery process. Given the ease with which the Synple automatable chemistry search configuration was implemented in SYNTHIA®, it is possible to extend this application to prioritize any subset of reactions that a specific user would preferentially like to use for their project. As such, SYNTHIA® has the potential to serve as a powerful tool for a uniquely customized and focused retrosynthetic analysis.
- Streamline Synthesis Planning: Learn how to use SYNTHIA® to customize search parameters for efficient route planning, reducing time spent on manual synthesis processes.
- Leverage Automation with Synple: Understand how integrating SYNTHIA® with SynpleChem automation technology accelerates the execution of synthetic routes, enhancing drug discovery efficiency.
Customize Reaction Prioritization: Explore how to extend SYNTHIA®'s capabilities to prioritize specific reactions, tailoring retrosynthetic analysis to meet unique project needs.
Speaker

Emma Gardener, Ph. D.
Technical Application Scientist
Emma Gardener received her undergraduate degree from Trinity College and worked for several years as a research associate in the biotechnology industry before completing her Ph.D. in Organic Chemistry at Brown University as an NSF graduate research fellow. She studied under Prof. Jason Sello, where she worked on developing new methodology for the synthesis of antibacterial peptide natural products. In 2018, she joined the Cheminformatics Technologies department of MilliporeSigma as a Technical Application Scientist and is responsible for the commercial licensing of the retrosynthetic design software, SYNTHIA®.

Benedikt Wanner
CEO, SynpleChem
Benedikt obtained his PhD in the group of Professor Bode at ETH, where he initiated the the platform Synple platform work. Subsequently, he has established Synple Chem as an automated synthesis company and is currently serving as CEO of the company.

Automated Synthesizer
Integrating SYNTHIA® with Synple's Automated Synthesizer streamlines synthesis, reducing time and effort while enhancing precision and efficiency.